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Any non-steroidal anti-inflammatory drug (NSAID) will decrease the inflammatory response that occurs with tooth movement. NSAIDs block prostaglandin synthesis and result in slower tooth movement. Prostaglandins have been found to play a direct role in bone resorption. Since the bone remodeling that is needed to move teeth is an inflammatory process, we recommend Tylenol (acetaminophen) so that it does not interfere with this process.
You cannot take any NSAIDs while correcting your smile with Invisalign. This includes Ibuprofen (Advil, Motrin), Naproxen (Aleve). This is because sit has been shown through different studies that NSAID drugs hinder the chemical reactions that are necessary during the process of applying pressure to teeth. NSAIDs reduce the important part of collagen formation used in strengthening the body's tissue and periodontal structure rebuilding. Please make sure that you are only taking a non-NSAID pain reliever.