In terms of the effectiveness of the Botox, and the results you will achieve, studies have not shown any difference when reconstituting with nonpreserved versus preserved sterile saline. The primary clinical difference is that preserved saline contains benzyl alcohol, which has some...
Dear beedee,
Thank you for your question.
Dimples are created from your facial animation muscles. Weakening your masseters may have weakened this in your case.
Do not worry. This effect is temporary. Your dimples will appear when the botox wears off.
I hope this helps.
Freezing the botox before the saline is added to it will most likely not decrease the effectiveness of the injections. Once the saline is added by your doctor it should not be kept frozen. There is no reason to believe this will reduce pain after the injections.