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In terms of the effectiveness of the Botox, and the results you will achieve, studies have not shown any difference when reconstituting with nonpreserved versus preserved sterile saline. The primary clinical difference is that preserved saline contains benzyl alcohol, which has some anesthetic properties (numbing), so it is theoretically a little less uncomfortable for the patient.
Botox can reconstituted with normal saline or with bacteriostatic normal saline. The bacteriostatic saline makes the Botox much less uncomfortable to inject as it acts as an anesthtic so we use bacteriostatic saline all of the time
Even though the FDA approved why to reconstitute Botox is with normal saline, most doctors use saline with preservative because it hurts less when injected. There have been no studies that I'm aware of that says the Botox is negatively affected by this.
Dear Mbrown.ma, The reconstituting of the Botox is done with preservative free saline. This is the guidelines set up by Allergan corporation and my surgical technician of over 25 years who mixes up my Botox always uses preservative free. Best regards, Michael V. Elam, M.D.
Dear beedee, Thank you for your question. Dimples are created from your facial animation muscles. Weakening your masseters may have weakened this in your case. Do not worry. This effect is temporary. Your dimples will appear when the botox wears off. I hope this helps.
Freezing the botox before the saline is added to it will most likely not decrease the effectiveness of the injections. Once the saline is added by your doctor it should not be kept frozen. There is no reason to believe this will reduce pain after the injections.
Neurotoxins such as Botox can relax muscles, but do not add volume, puffiness, or cause "chipmunk cheeks." When assessing the human cheek, there are certain contours that must be respected. If they are violated with fillers, the cheeks look unnatural and distorted. Expert injectors know where to...