I think the way you have put this, the answer really boils down to your personal preferences as far as a one stage procedure or two. In general, we typically like patients to have most if not all of their weight loss complete before doing breast surgery, at least anything definitive like lifting or reduction. Your breasts will likely change with weight loss, and we can't predict how much, thus with surgery now before weight loss is complete, you are "shooting at a moving target." If there is some reason why you would be more comfortable getting your implants out now, say they are getting in the way of exercise, it is reasonable to do that alone as a first stage prior to weight loss. This will also have the advantage that sometimes the breasts will contract and "settle" on their own following explantation alone, and this may allow for less of a lift in the end. Just understand that with this option you may be committing to a second stage procedure down the line once the weight loss is finally completed and the breasts have settled. Alternatively, you can wait until your weight loss is completed and undergo the entire procedure as a single stage. This has the advantage of getting everything done at once, but there is more "tailoring" to do as the implants are coming out and the lift is being done at the same time, and accuracy may be sacrificed. Regardless, the one option that I would strongly recommend against is having the operation done in its entirety now before you lose weight. If you have any surgery now before weight loss, the only thing I would suggest at this point is the explantation of the existing implants. On balance, if I had to pick my favorite of those two options, and I had a patient who was amenable to considering a two stage procedure, I might select the two stage approach with removal first followed by the more definitive procedure as a second stage after weight loss, because this allows nature the maximum opportunity to help us out and it may cut down on what we need to do to the breasts, thereby eliminating some element of human error. I suggest you take this information from RealSelf and visit a board certified plastic surgeon with experience in revision breast surgery to get his or her input and advice. Good luck.