All of these treatments will remove fat permanently so there is no difference in duration of results. CoolSculpting is definitely the safest since it is non-invasive while the others are minimally invasive. However CoolSculpting will remove approximately 20% of fat in the treated area, while LaserLipo and liposuction procedures can remove more or less fat in the treatment area, since these treatments are much more customizeable than CoolSculpting. I would say that depending on the amount of fat and skin laxity present, the potential for best results is higher when LaserLipo or liposuction are done because of the ability to customize the treatment very specifically. That being said, I think that the experience of the physician performing each treatment as well as the expectations of the patient are the most critical factors in achieving the best results. I would suggest a consultation with a cosmetic physician experienced in CoolSculpting as well as LaserLipo and liposuction to help you determine the best options for your concerns. Best wishes, Mary Beth Mudd