Can I start using doxycycline two weeks after using Accutane 20 mg for 8 weeks?

Question

I did 8 week course for 20 mg Accutane ..two weeks after stopping Accutane (epiris) my sking in all red with severe dryness and small pimples on my face. Can I start doxycycline to get control of the condition? I have used low dose doxy for years

Amy Y. Paul, DO, FAAD · Answer

Thanks for your question. I would definitely check with your own dermatologist first, but you might need to wait until 4 weeks post accutane to take doxycycline.  We don't clear patients to attempt pregnancy until after the 4 week "wash out" period after their last dose of accutane, so there is still a chance there is a little residual accutane in your body.  You wouldn't want to risk the combination, so my personal advice as a dermatologist who prescribes a lot of accutane is to wait another 2 weeks.  In the meantime, try a mild salicylic acid wash, maybe a topical antibiotic such as clindamycin or a sulfa prep or mask.  You could also see a good aesthetician that works with dermatologists for a light salicyclic acid peel for a quick clean-up.  Best of luck!

F. Victor Rueckl, MD (in memoriam) · Answer

The two should NOT be taken together. I also question why you only took 20mg Accutane for 8 weeks. That's only a total cumulative dose of 1200mg which is far from an effective dose. I would suggest a visit with your dermatologist to go over everything and would not resume Doxy until speaking directly to your prescriber. Something is off. "This answer has been solicited without seeing this patient and cannot be held as true medical advice, but only opinion. Seek in-person treatment with a trained medical professional for appropriate care."

Reuel Aspacio, MD, FAAD - Account Suspended · Answer

Thank you for your question. Accutane and doxycycline can affect the liver and should not be taken together. With that being said, Accutane can remain in the body for weeks after stopping, so I highly recommend you consult with your dermatologist regarding when you can start doxycycline. Take care and good luck.

Can I start using doxycycline two weeks after using Accutane 20 mg for 8 weeks?

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Can I start using doxycycline two weeks after using Accutane 20 mg for 8 weeks?

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Everything you need to know about Accutane

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