Lasers have really almost entirely done away with chemical peels for the treatment of wrinkles. On the whole, one can achieve far greater results with far better control utilizing a laser. The real questions most patients need to consider when looking at one treatment over another (say different lasers) is 'What is my desired result?' and 'What is my tolerance for downtime?'. It can be a challenge to balance the two questions and in the end, more downtime usually equates to more result, faster. Certainly, more gentle treatments with lesser amounts of downtime can eventually lead to good results, however, the trade-off is often a series of procedures v one. Deep resurfacing with erbium, or CO2, is the gold standard for deep lines. Most patients would consider the downtime involved to be fairly extensive and the redness of the treated areas to be fairly prolonged. The results are beautiful and this is usually a one and done treatment. Not every patient is a candidate for deep resurfacing due to skin type. Fractional lasers are basically all going to require multiple procedures stacked a couple months apart to get to a nice result. A patient's hide out time is generally much shorter and easier to conceal overall. By the time you consider multiple treatments, the costs of fractional resurfacing vs. deep can be fairly even. And, sometimes a filler is still needed to augment the result. And, often patients should consider neuromodulators (Botox, Dysport, etc.) to help maintain the result. The answer isn't necessarily quick and easy. Best! Dr R