What is the best treatment for wrinkles on my knee? (Photo)

Thank you for your question!  Botox and fillers are a good option to help with the wrinkles in the knees.  Ultimately, you'll need an in-office consultation with a skilled provider to determine which product is best for you. All the best!

Knees are a tricky area, and a physical exam will be necessary to determine if this will result in improvement based upon amount of fat and the skin laxity present.  This area is more prone to contour irregularity after liposuction, and as such liposuction should be limited.  You also do not want to have an issue with falling skin. 
Another option might be computer controlled BodyTite which is safe with regards to the risk of burning as the energy delivered from the liposuction cannula tip is turned off by the computer when the optimal temperature is reached.   Melting and removal of the fat by the canunula provide durable long term results with significant skin retraction and without scarring and long down time.  
Kenneth Hughes, MD, Board Certified Plastic Surgeon
Los Angeles, CA