Hello! My name is Jessica, I am a physician assistant, and one of the providers at Aesthetic Skin in Winnetka and Chicago. This is a great question. If dissolving your lip filler with hyaluronidase has resulted in significant volume loss and a noticeable change in your appearance, there are several steps you can take to address these concerns and restore facial volume. First, consider revisiting a skilled cosmetic injector to explore options for replenishing volume with new dermal fillers. Hyaluronic acid fillers can help recreate the fullness in your lips and surrounding areas, bringing back a more balanced and youthful appearance. Additionally, Sculptra could be beneficial for stimulating your body’s collagen production, which gradually restores volume and improves overall facial contours. If you are concerned that the changes are more extensive and involve overall facial sagging, consulting with a board-certified plastic surgeon for a thorough evaluation might be warranted. They can assess whether a surgical intervention, such as a facelift or other contouring procedures, would provide a more comprehensive solution to address significant volume loss and sagging. Combining these approaches with ongoing care and tailored treatments will help achieve the best results and restore your confidence in your appearance. I hope this helps and best of luck!