Can lumps/swelling from kybella be permanent ever?

In almost all cases the lumps resolve, although they may take awhile before they do. Low intensity shock wave treatment is what I use when I encounter post treatment swelling and lumps.

Kybella (Deoxcholic Acid) is the first non-surgical, FDA approved injection to reduce submental fat. Some of the side-effects include bruising, swelling, redness and numbness, though most tend to subside over time. To reduce this we as patients to discontinue any blood thinners prior to their treatment, and recommend an anti-inflammatory post treatment. Treatments are done once every 4-6 weeks, for up to 5 sessions.
Always discuss these possible side-effects prior to treatment.