Difference between hyalourondise and vitrase?

Hyaluronidase is the generic name for an enzyme that can be used to dissolve hyaluronic acid fillers. Vitrase® is one of multiple brands of hyaluronidase. The use of this product to correct HA filler mishaps is considered "off label."  This means that there is no official FDA approve protocol for using hyaluronidase to dissolve fillers. Practiontioners who use this product to dissolve fillers use techniques that they have either developed on their own through years of experience or have learned from other practitioners. The bottom line is, the dose, brand etc. is not what the consumer should be worrying about. What you should really be concerned about is how experienced the injector is in using this product. 

The two options you are referring to have various differences. Vitrase is an ovine (sheep) derived enzyme,  with a strength of 200 Units per 1 mL.  Hylenex is a human recombinant enzyme with an activity level of 150 Units per 1mL. They are both a hyaluronidase enzyme that will break down hyaluronic acid. The most commonly used preparation is usually Hylenex, with dosages varying upon amount of filler needed to be dissolved. The strength per mL of either is not reflective upon the effectiveness.  I hope this helps!!
Michelle Giglio, PA-C

Both have the same ingredient. The concentration is different. So the amount of drug will vary by volume used for each. How much someone will need varies in a case way. In general, the number of units used is usually very very small.