I don't use Acell, so I can't speak to its effectiveness. PRP is showing more and more promise with new research studies being released showing that it is effective for a variety of hair loss applications, including male-pattern baldness. Due to these studies and my own experience with my patients, I do believe that PRP works for hair loss. It is not a substitute for a hair transplant, but can be a nice bridge to a transplant, a supplement in a post-hair transplant patient, or a non-surgical option for patients who are not interested in a transplant. Side effects include bruising and swelling primarily. Infection is a potential risk, but not something I've seen. Discomfort or a mild headache are also a possibility. All of these side effects are usually very mild. All the best,