Thank you for sharing your concerns and photo. It looks like you’re dealing with residual scarring from long-standing acne, along with some active breakouts. Since you’ve already tried multiple medical and procedural options (topicals, antibiotics, spironolactone, isotretinoin courses, Morpheus8, CO₂ laser), your situation falls under refractory acne and acne scarring, which can be very challenging but not hopeless. Here are some tailored considerations: Active Acne Control Even after multiple treatments, some people benefit from combination therapy (hormonal + topical + procedural). Topicals with retinoids (tretinoin, adapalene), azelaic acid, or dapsone gel may help ongoing breakouts. If hormonal triggers are suspected, sometimes adjusting spironolactone dose, or adding other hormonal regulation, can help. Scarring Management Subcision (to break up tethered scars) followed by collagen-stimulating treatments can give noticeable improvement. Microneedling with PRP or radiofrequency microneedling sometimes works better when alternated with subcision. Fractional lasers (erbium or fractional CO₂) in staged sessions can continue to remodel scars, especially when combined with filler or biostimulatory injectables (e.g., Sculptra, Radiesse). Skin Texture & Boosting Collagen Collagen stimulators or dermal fillers placed strategically can help elevate depressed scars. Topical growth factors, peptides, and retinoids are supportive in between procedures. Emotional & Functional Aspect Persistent scarring often affects confidence as much as appearance. Many patients benefit from knowing that multi-modal, stepwise treatments — not one single fix — usually achieve the best results. Summary: At this stage, the best approach is usually a combination plan targeting both the scars and any ongoing breakouts, often including subcision + biostimulatory fillers + microneedling/laser resurfacing, while maintaining acne suppression with topical or hormonal therapy.