Is it better to use minoxidil 5/with PRP or it may be come with negative effect?

The answer is yes, the more you can do to stimulate your hair follicles the better.  This includes1. PRP hair injections2. LED laser cap home treatments 2 to 3 x per week3. Topical 5% Minoxidil (sometimes even oral)4. Propecia (in men)5. Vitamin supplmentation such as Biotin and Vitamin DThey all work together to give you optimal results.

PRP and minoxidil can be used together. I frequently will recommend that patients try minoxidil, finasteride, PRP, and other non-surgical treatments together. These treatments work by different pathways, so they may have a combined synergistic effect if used together to improve hair density or slow hair loss. These treatments can also be used in conjunction with a hair transplant procedure.
All the best,

Ask your doctor if you want to use minoxidil and PRP. There are no studies on PRP with minoxidil. They are two different types of treatment.

As with most conditions, combined therapy may have some advantages.We DO combine PRP with Minoxidil 5% at least once a day. The studies from Europe are with PTP alone since there can only be one variable.  However, Our center recommends PRP with Minoxidil and any other appropriate adjunct such as Propecia and skin microneedling home rollers.

No studies have ever been done in this exact question but I often advise use of both PRP and minoxidil in select individuals with genetic hair loss. PRP is packed with about 20 follicle stimulating chemicals and minoxidil is packed with 1 follicle stimulating chemical. 21 is always better than 20 !