Can Retin-A help loose upper arm skin?

While Retin A (and other topical retinoids like it) is helpful for promoting new collagen and elastic fiber synthesis, and is useful for improving many different kinds of skin tone and texture problems, it is very unlikely to have any significant impact on loose upper arm skin. Surgery remains the definitive treatment for this condition, but, as a major drawback, unfortunately leaves an unsightly, long, linear scar on each armLasers, radiofrequency devices and ultrasound machines have all been marketed for this purpose, but, with all these, the results tend to be disappointing, variable and inconsistent. Relatively recently, a Body Vectoring Technique, using an injectable volumizing filler, Radiesse, was developed in Europe and was found to be helpful for treating loose upper arm skin, as well as loose inner thigh and abdominal skin. The technique relies heavily upon the biostimulatory effects of the Radiesse (i.e. the materials ability to stimulate new, native collagen and elastic fiber synthesis--neocollagenesis and neoelastogenesis). In my experience, biostimulatory volumizers, like Voluma XC (New York City practice), Teosyal Ultra Deep, Emervel Volume (Israel satellite facility) may likewise be used. The injection technique employed for Body Vectoring is a modfication of the technique used for The Nonsurgical 3D Vectoring Facelift and takes only about twenty minutes to perform for treating both arms. To learn more about The Nonsurgical 3D Vectoring Techniques, check out the archives of Realself.comConsultation with an experience injector is a must. 

Retin A cannot tighten, it can only help fine lines.  Sculptra and Thermage followed by venus legacy or velashape are my best combination to fight wrinkling arms.  ThermiRF is a good surgical option.  Best, Dr. Emer.