Can your body reject botox after long term use?

Botox should last 3-4 months, if it doesnt continue to last, then a change in dose or product may be needed.  Best, Dr. Emer.

Thank you for your question. Botox should last on average 3 months. Botox dosing might require adjusting as your face changes over time. All the best,

In my experience,  when Botox isn't lasting long enough, the dosing needs to be increased. There is sometimes a resistance that builds up, and I try switching to Dysport to see if this makes any difference. If it is the same in all your friends simultaneously,  then it's probably related to changes in dosing by your doctor or he/she is getting the Botox from a different or illegal source. Sometimes a very athletic person burns up the Botox quicker I've seen.