Can 2% ketoconazole shampoo damage the hair in long term use?

Question

I read Nizoral with ketoconazole 2% is an anti-dandruff shampoo which could contribute to slow down hair loss. But is it really safe for my hair in the long run if I use it as an hair loss treatment (1-2 times a week)? Thank you

Jae Pak, MD · Answer

Ketoconazole is an anti fungal medication.  There is a "theoretical" anti-androgen property so many people use it for hair loss.  But clinically I have not ever seen it work.  In fact, it may irritate the skin.

Jeff Rapaport, MD · Answer

Nizoral shampoo (Ketaconazole) can  partially block DHT receptors. To be effective, it needs to be utilized every day. Unfortunately,  it can be irritating to the scalp. Therefore, I agree with dr. Rassman, one to two times a week is probably not very useful.Jeff Rapaport MD FAADRealself All-star

Yael Halaas, MD · Answer

Nizoral is safe to use and is commonly recommended for dandruff. There are some mild benefitsto its use for combating hair loss particularly in combination with a regimen including minoxidiland other topical ingredients. It can be safely used for long term use.

Sara Wasserbauer, MD - Account Suspended · Answer

Nizoral is a shampoo that I recommend quite often. It is safe to use 1-2 times a week. Gives the scalp a healthy place for the follicle to grow.

William Rassman, MD (retired) · Answer

I don't believe that Nizotl with 2% ketoconazole shampoo will damage the hair; however, I don't think that this has any value for genetic hair loss

Can 2% ketoconazole shampoo damage the hair in long term use?

Answers (5)