How soon can I drive home after upper eyelid surgery? 1300 mile round trip.

I would want you to follow up about 5 days after surgery to have your sutures removed.  If it all looked good at that point I'd be fine with you traveling

This all depends on level and type of anesthesia and what medications your are taking after and the level of swelling afterwards.  

It is entirely something else to have to drive 1300 miles.  I would encourage you to fly this distance.  At a minimum you should stay close to your surgeon the first week until all sutures are removed before making such a drive.  Even then, I do not think such a drive is realistic.

Follow-up with your surgeon is of the most importannce, so probably plan on spending at least a week in that location. It is totally acceptable to fly/drive home at that point. Plan on following up with your surgeon in a month or two after the surgery.

I assume you are referring to Upper Blepharoplasty.  As stated previously, you could be driven (by a responsible adult) home the day after surgery.  I would not advise this as it would be wise to remain near your surgeon for the first week after surgery in case any complications were to develop.  I would not advise driving yourself on a long trip like you propose for at least 1-2 weeks after surgery.

Every surgeon has different rules. In my practice, I allow patients to start driving on day 3 or 4 with the reason being that they use an antibiotic ointment day and night for the first 3 days and then at night only. Using the ointment properly, it would be impossible to drive due to the blurry vision - especially such a long distance. Also, please remember than while upper blepharoplasty is a fairly minor procedure, you will not feel completely "back to normal" and able to drive long for a minimum of 6-8 hours. Please do communicate with your surgeon and let him/her know the situation 

You can easily be driven home the next day. Otherwise if you are driving you need to wait for the swelling to go away. You would then have to turn around for another round trip for your followup and suture removal a few days later.