Is it possible to soften fat before liposuction?

There is nothing that you can personally do prior to liposuction. However, you sound like an ideal candidate for laser or ultrasound-assisted liposuction. Both of these energy devices can help break up the connective tissue during the liposuction procedure, which "loosens" up the fat cells, and make liposuction of fibrous areas more effective. 

there is no need to soften fat with HD liposuction as the energy devices can work around this and still get you amazing loss of fat, skin tighteing and contouring.  Best, Dr. Emer.

Liposuction can be combined with either laser or ultrasound to dissolve the fat prior to removal with suction.

There are anatomic areas that are consistently more fibrous in women: the upper back especially bra rolls, and the fat around the belly button. Fibrous fat cannot be changed to fluffy fat.  Upper back liposuction can be successful if there is significant fat in that area and the surgeon suctions aggressively.  This is not an easy area to suction. 
Numerous plastic surgeons in LA, including my own practice, are offering the BodyTite radio-frequency assisted lipolysis with exceptional surgical results without the excision, scars, or downtime.  Sedentary activities can be resumed in two to three days and full activity with exercise within two to three weeks. 
Kenneth Hughes, MD, Board Certified Plastic Surgeon
Los Angeles, CA

In areas which are more fibrous or scarred down, certain cannulas with specially designed tips are used to soften the fat and release some of the tethering cords and harder tissues to make the liposuction more smooth and easier to perform. This is done during the procedure by the surgeon so there is nothing to do prior to your surgery. Hope this helps!Johnson C. Lee, MD Plastic Surgery@drjohnsonlee

There is not really an external modality that would change the nature of the fibrous fat to softer fat. How do you know you have "fibrous" fat? There are anatomic areas where fat tends to be more fibrous in everyone - the male breast, the back, the saddlebags, for instance - but it's unusual for a patient to be told (s)he has fibrous fat in general.Theoretically, your surgeon might consider having you undergo ultracavitation and/or lymphatic massage preop, though these are overwhelmingly more commonly used postop to control swelling and shaping. In surgery, the surgeon could use Vaser (ultrasound) assistance, which is a main modality to help deal with fibrous fat or simply to make it easier to harvest fat in general. The downside is that ultrasound could damage fat cells that would be transferred (say in a BBL procedure), so if you are having fat grafting, you may simply need to accept the risk that if your fat is indeed fibrous, it may be harder to inject and hard to know how much will take.

I am not aware of any effective means of "softening fat"  prior to performing liposuction.  There are certain areas on one's body that may have more fibrous fat, such as back rolls.  Some plastic surgeons may consider using other adjunctive means to treat this fat during the procedure, such as the use of ultrasonic liposuction, which "melts" some of this denser fat and makes it easier to then remove with traditional techniques (SAL).  I would discuss your questions with the board certified plastic surgeon that you choose.  Best wishes!

that cannot Fat cannot be changed before liposuction. For those with high degrees of connective tissue in there fat certain tools like VASER may be beneficial.For the most part it's simply a matter of the surgeon working harder and performing liposuction for longer periods of time to  remove fat that has more connective tissue.Best,Mats Hagstrom,MD