Will Hyaluronidase injection to dissolve Juvederm affect natural volume in my lips?

Hylauronidase has many advantages and should be considered in patients who are unhappy with their results or in acute cases of overfilling or occlusion. Its often better to reverse filler and restart then to deal with long term edema. Filler migration and permanence is a very common problem because there are many different types of HA fillers on the market and each is specified for a specific part of the face. Use of highly cohesive fillers on thin skin may cause swelling and nodularity. If patients have filler migration or nodules, we recommend a combination approach of filler reversal with enzymes Hylenex and Hyaluronidase in different strengths to dissolve the filler. We may also need to add Kenalog to the mix in order to reduce fibrous tissue. If the filler does not dissolve, it either means the filler is not HA material or we need more enzyme. The HA reversal can be combined with other lasers and skin treatments at the same time, and it usually (usually) does not affect adjacent tissue.

Best,
Dr. Karamanoukian
Realself100 Surgeon

In most cases, only a small amount of hyaluronidase is used to limit the amount of filler that is dissolved. In fact, a step-wise reduction can be performed to prevent all the filler from being removed. The hyaluronidase will not take away your natural volume. In the future, you might consider using some of your own fat or "fat transfer" to add volume to your lips. Fat is soft and supple though it does not provide a longer result.

Hi T,I would recommend consulting with an injectable filler expert physician to correct your concerns.  I usually prefer to smooth any irregularities and only use hyaluronidase if absolutely necessary.  Too much filler can be lost, and in some cases there can be some loss of the patients natural volume. It is difficult to answer your question accurately without seeing photos.  Good luck and be well.  Dr. PEncino, CA 

Thank you for your question. Using Hyaluronidase to dissolve lip filler will not affect your natural, pre-filler volume. It may, however, dissolve more of the filler than desired. If you decide to go ahead with dissolving the product, you should be prepared in the event that it dissolved more than you wanted. This is why it is so important to have an in-person consultation and evaluation where a discussion can be had in detail regarding the dissolving of filler and it can be determined whether it is actually the best course of action for you. Make sure you are under the care of an experienced physician.

Hi,The hyaluronidase will not have an effect on the native lip tissues. I do agree that it is difficult to control the amount of filler that is dissolved if you are looking for a slight volume reduction. It is very likely that in the next couple of weeks your lips will shrink about 10-15% so waiting seems like the best option.Best,

Thanks for your question. I find it very difficult to control how much of an injected HA filler is dissolved when hyaluronidase is injected.  I am not concerned about your natural lip volume being altered, but you may lose more of the "filler effect" than you bargained for. I recommend you are carefully evaluated by a skilled physician injector to see what options might be available to you. Best of luck!

It's hard to control how much of the filler will be dissolved using hyaluronidase so you maybe left with less filler then you like. Hyaluronidase should not affect your normal HA over the long term (few days out). 

Hyaluronidase is difficult to control in regard to reducing volume evenly after filler placement. It will not effect the natural lip fullness. I'd consider waiting until the effects have self resolved in 9-12 months or remove the filler entirely. 

Hyaluronidase is an enzyme that dissolves hyaluronic acid (HA). It will only remove HA based fillers and will leave the natural tissues intact. There may be some swelling for a few days after it is injected.

Using Hyaluronidase has a possibility to dissolve more volume then needed.
The lumps will go away in a few days so depends on your comfort level I will leave it alone because you many not like the dissolve of the and will ask for more fillers that would cost you more money 
So basically I would wait a week or so before making the decision to dissolve them.