This is a very good question, and perhaps one of the major reasons results vary so much.Here is the key to success. Why do our best results occur with thin patients and not with heavier patients? The reason is that in thin patients, their fat is mainly composed of cells that are not full of oil. As the patient gains weight, their fat cells become large and full of oil, which makes them even more vulnerable to rupture during harvesting and transfer, which is the reason the absorption rate and final volume is lower.Therefore for the same volume (cc of fat injected), the fat of heavier patients will contain more oil and less fat cells per ml. This is the reason I ask all my patients to not gain weight, but rather loose weight prior to the procedure. I can then transfer more fat cells per ml that will survive the harvesting and transfer. This leads to the original question about weight fluctuations after the procedure. If you gain weight afterwards, the fat cells that survive will enlarge and become full of oil, which will make your breasts bigger. However, what if you loose weight? The small fat cells that are not full of oil will remain stable, and will not get smaller, so you can expect the size of your breasts to remain the same. The fat in the rest of your body that has preferentially larger fat cells with oil will get smaller. If you go into a state of starvation, then the fat cells will start to break down to provide your body with fuel for survival. Therefore with weight fluctuations after fat transfer breast augmentation will only lead to you breasts getting larger if you gain weight, but will tend to stay the same if you loose weight. Unless you go into extremes.Hope this helps!