What is the difference between Restylane Lyft and Sculptra?

Doctor Answers 12

Difference Between Restylane Lyft & Sculptra

Hello.  Restylane Lyft is a new name for Perlane, a Hyaluronic acid based dermal filler that is injected into the skin to provide volume.  Lyft is one of the most basic fillers in that it is made out of a compound that is already in our body- Hyaluronic acid.  It is easy to use, safe and is injected into the second layer of skin, the dermis.  One of the primary benefits as compared to Sculptra, is that the result of the treatment can be seen immediately.  It lasts about 8-10 months, which is less than Sculptra.

Sculptra is not a traditional dermal filler, but rather a biostimulator.  It is a fine powder that, when mixed with saline and injected, stimulates the production of collagen.  Because Sculptra stimulates your own collagen production, it takes a lot longer for the results to be seen.  In our practice, approximately 6-9 months after the first visit is when peak improvement can be seen.  The product lasts approximately 2 years.

Finally, Sculptra is generally more expensive than Restylane Lyft, but we love the natural looking results that Sculptra offers.  

Los Angeles Facial Plastic Surgeon
4.5 out of 5 stars 8 reviews

Restylane Lyft vs Sculptra

Lyft is an HA product. It will give immediate results that will last a year or more. Sculptra is PLLA, which cause collagen to create the fill. It is done in a series of 2 or 3 treatments, and will last 2 or more years. The results take several weeks to take effect. Sculptra will treat much more volume loss for the cost of Lyft, about 4 times as much. I love both, and if you can wait for results, Sculptra is going to be more economical and longer lasting. It will fill more deficit.

Steven F. Weiner, MD
Panama City Facial Plastic Surgeon
4.6 out of 5 stars 26 reviews

Restylane Lyft versus Sculptra

Restylane Lyft and Sculptra are both Galderma products.  Restylane Lyft is a hyaluronic acid filler like Restylane, Voluma, and Juvederm.  Restylane Lyft is approved for the midface and cheek areas.  Sculptra is also used to augment the cheek areas but this product is different in its chemical composition.  Sculptra is a poly-L-lactic acid product which is diluted and injected in higher volume amounts.  It has FDA approval for medication induced facial lipoatrophy but is used to for facial augmentation.  

John Burns, MD
Dallas Plastic Surgeon
4.6 out of 5 stars 31 reviews

Restylane Lyft, Sculptra and Filler Differences


Restylane Lyft (rebranded Perlane) is a hyaluronic acid (HA) gel filler with moderate projection and moderate volumizing effects. HA's, I find have very little inflammatory collagen building effects. 

Sculptra, while categorized as a filler has more distinct bioactivity. Sculptra is a suspension of poly-L lactic acid. It seems to stimulate production of structural molecules of the tissues it is injected into such as collagen, elastin, HA and others. It appears to stimulate regeneration of cells and a provide a more rejuvenated skin surface as well. 

While Lyft is filling and projecting, Sculptra stimulates more firming and resistance qualities to the skin. 
Lyft effects are immediate and Sculptra takes 3 months or more to peak in activity. 

Many other fillers are available to be reviewed with your Board Certified Injector. All the best!

Dean P. Kane, MD, FACS
Baltimore Plastic Surgeon
4.8 out of 5 stars 67 reviews

Restylane or Sculptra

Restylane is a traditional hyaluronic acid filler.  It lasts about 6-9 months.  The results are visible immediately.

Sculptra is not a traditional filler.  It stimulates your own body to produce collagen.  Therefore, the results are not immediately seen, but can take weeks.  However, the results last about 2 years.

Always seek treatment from a qualified professional.  Good luck!

Jennifer Trent, MD, FAAD
Sarasota Dermatologic Surgeon
5.0 out of 5 stars 4 reviews

Restylane Lyft is a hyaluronic acid filler that provides immediate results that can last from 8 to 18 months.

Restylane Lyft is a hyaluronic acid filler that provides immediate results that can last from 8 to 18 months. Sculptra is a poly-L-lactic acid collagen building filler that works by stimulating the body’s own collagen production. Sculptra results will not be seen immediately because it takes time for the body to replenish its collagen supply, but after they appear results can last for up to two years. To decide which option is better for you, please see a board-certified dermatologist who offers both products.

Margaret Weiss, MD
Baltimore Dermatologic Surgeon
3.7 out of 5 stars 7 reviews

Restylane Lyft versus Sculptra

Restylane Lyft is a hyaluronic acid.  This product is available in a 1 cc syringe.  It is a clear gel.  Lyft is injected to a specific area (FDA approved for cheeks).  Immediate volumization is apparent.  The result may last up to one year.  

Sculptra is also an injectable, but is totally different than Lyft.  Sculptra is a mixture of a chemical and water.  Following injection, the face is volumized by water, but the water is absorbed within 1-2 days and poly L lactic acid remains in the collagen, which continues to stimulate and thicken the collagen.  Therefore, we describe Sculptra as a global treatment, thickening the dermis.  Usually 3 treatments are required, approximately 6 weeks apart. 

We, many times, recommend Lyft and Sculptra for the same patient, injected on different days.  These are both wonderful products.

Marc J. Salzman, MD, FACS
Louisville Plastic Surgeon
4.6 out of 5 stars 38 reviews

The Difference between Sculptra and Restylane Lyft

Sculptra and Restylane Lyft are typically used to increase facial volume.  They are completely different.  Restylane Lyft is a hyaluronic acid that has immediate results whereas, Sculptra is L polylactic acid that slowly stimulates the body to produce collagen.

Craig Mezrow, MS, MD, FACS
Philadelphia Plastic Surgeon
5.0 out of 5 stars 15 reviews

Sculptra vs. Restylane Lyft

Restylane Lyft formally known as Perlane is an FDA- approved hyaluronic acid filler with a large particle size that treats midface contour deficiencies when injected into the deep dermis. The correction of sagging cheeks and mid-face helps to decrease the appearance of nasolabial folds, marionette lines and jowls. Restylane lasts about 8 months to 1 year.

Sculptra™ is an FDA-approved injectable product that restores and corrects the signs of facial fat loss by replacing lost volume. Sculptra is composed of poly-L-lactic acidwhich is a similar substance used in dissolvable stitches and various soft tissue implants. Sculptra works by filling in hollow areas and by stimulating the body to produce collagen and underlying tissue for a long-lasting, natural and youthful look. By filling out the deflated skin, the sagging face appears tighter. Sculptra can last up to 2 years.

Sculptra is different than Restyalne in that it is a bio-stimulant to produce your own collagen so it will take a few months to see the results. Restylane is a Hyaluronic acid which gives you immediate results. They are both great products. An in person consultation with your plastic surgeon is necessary to determine which product is right for you.

Laurie A. Casas, MD, FACS
Chicago Plastic Surgeon
4.9 out of 5 stars 86 reviews

Restylane Lyft vs Sculptra

Thank you for this question.  I often combine these products to when I plan a more lholistic approach to non-surgical facial rejuvenation.  Restylane Lyft is ideal for lifting the cheeks and helping to soft the nasolabial folds and the marrionette region.  It is a hyaluronic acid based filler and can last a good year depending on the amount used.  Sculptra is also used to help restore volume along the sides of the face and along the jawline.   I would recommend visiting with a board certified plastic surgeon or dermatologist who specializes in Sculptra and the Restylane portfolio of products.

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.