Erythromycincan be taken safely after Botox injection. There have been no studies showing a significant interaction between Erythromycin (a Macrolide antibiotic) and Botox.On the other hand, Aminoglycoside antibiotics (amikacin, gentamicin, kanamycin, neomycin,netilmicin, paromomycin, streptomycin, and tobramycin) may increase thepotency of Botox.