After the laser treatment, Will it affect the blood circulation within the body? (such as blood clot)

I have got cucumber sized black shadow tattoo on my calf, So if I use like any laser treatment (esp. Picosure & Q laser) for over 10 treatments, will it affect the blood circulation in the body like blood clot which is very dangerous, Also what about the skin cancer that might cause in relation to how the laser treatment is done?