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I would start with a good moisturizing cream for the area around the mouth, which includes Elevase Moisture Booster with ceramides. Apply the area liberally with moisturizer and this will help support your skin's natural moisture barrier function. Best, Dr. KaramanoukianLos Angeles
I recommend Aquaphor ointment. It is tasteless and extremely protective and moisturizing. Aquaphor is available over-the-counter and is inexpensive.
This is a common question from patients on Accutane. Your best recourse is to prevent the severe lip dryness by keeping some lip balm in every pocket and every backpack you have. My patients really love Dr. Dan's Cortibalm, and order it online. Some like Carmex, and more girls than boys like Aquaphor (which can be shiny). Any lip balm needs to be frequently reapplied. One you can get at music stores is called "Chop Saver" and is a citrus flavor. You can also try a humidifier in your room at night, and try not to bite or pick the lips while on Accutane. Best of luck!
For me, the standard go-to product has been Dr. Dan's lip balm. However, there is a new topical moisturizer designed for lips called Epiceram-L. It works great without the hydrocortisone that is in Dr Dan's balm. It can be dispensed directly by your dermatologist.
I usually recommend Dr. Dan's cortibalm or Aquaphor to treat the lip dryness associated with Accutane. The key is to apply it often, as many times as you can remember. Carry it around in your pocket!