Dysport, like the other types of neuromodulators available (Xeomin, Botox), is thought to require approximately 48-72 hrs to begin seeing a near-full effect because the toxin needs to be taken into the nerve cell endings. Once the dysport is inside the nerve ending, it acts rapidly to create its effect and the laser radiation should not interfere with that. As a result, I usually recommend that my patients wait 1-2 weeks before having laser resurfacing, for example, such that the result is both maximal and unalterable (by the laser). Theoretically, the inflammation generated by the laser may act to increase the metabolism of the dysport, but this is only in theory. Certainly, after two weeks you should be fine. Best wishes!