Q 1: What are the treatments options for painful labia minora following trimming labioreduction and Q2: Is PRP effective and safe for pain associated with labioreduction? A 1: Trimming the labia minora (a straightforward amputation) should not be used as a surgical intervention for labioreduction of the labia minora because a) often results in over-resection leading to labial neuropathy (pain at the incision site) or pudendal neuralgia (pain in the multiple areas that is innervated by the pudendal nerve) is the result of the referral pain from the original surgical site); b) permanently changes the natural shape and look of the labia minora. In the case presented here, most likely, pain is related to labial over-resection. When a surgeon resects the labia minora above Hart’s line, that demarcates a transformation from smooth transitional vulvar skin to vulvar skin and is located on the inner surface of the labium minus is well visible during a medical examination. Such resection can result in pain that may trouble a patient for the rest of her life. In the case presented here, most likely, the surgeon over-resected labia minora. Usually, over-resection of the labia minora requires a corrective surgery that I performed in two separate stages under local anesthesia in the office. Stage I - is the tissue-expanding-elongating labia minora materials (no classic skin-expanding materials are used). Stage II - removes tissue-expanding materials, and I perform cosmetic surgery on the labia minora in harmony with a patient’s request. Offering labial wadge resection or additional trimming can worsen the pain. A 2. There is no single scientific-clinical published research in the medical literature that references the safety and effectiveness of Platelet-Reach-Plasma (PRP). Additionally, FDA has not specified the labia minora therapy with PRP for postoperative labial treatment of pain. Therefore, I do not recommend using PRP for these medical indications. With regards, Prof. Dr. Adam OstrzenskiUS Cosmetic Gynecologic Surgeon