Does taking Benadryl affect longevity of Botox results?

Question

I get Botox regularly and sometimes take Benadryl to sleep at night could taking Benadryl affect how long my Botox last?

Muhammad Mirza, MD (license suspended) · Answer

Thank you for your question.  Antihistamines would not interact with the longevity of Botox.  Best regards

Ron Shelton, MD · Answer

Benadryl antihistamine does not affect the effectiveness or duration of Botox. There should be no concern that you will have a negative consequence having had Botox should you take Benadryl in the evening to help you sleep.

Scott C. Sattler, MD, FACS · Answer

I'm not aware of any relationship between benadryl and Botox - the medications work on different systems and are metabolized with different physiologic pathways.

David Hansen, MD · Answer

You can continue taking benadry since it has no effect on your botox results or its longevity.

Jason Emer, MD · Answer

Thank you for your question, Botox results last up to 3-4 months, there is no correlation between Benadryl affecting the longevity of Botox. I hope this was helpful. Best, Dr. Emer.

Camille Cash, MD · Answer

Taking Benadryl will not impact your Botox treatment or longevity.  Botox wears off gradually over three to four months on average.  I've included a video about neuromodulators that I hope you find helpful.

Carmen A. Traywick, MD, FAAD · Answer

Botox lasts up to 3-4 months. There is no correlation between Benadryl affecting the longevity of Botox. Hope this helps.

Ghazwan Sharabi, MD · Answer

Pharmacologically speaking these two medications (while both affect the nervous system) are operating on a completely different targets within the nervous system. So by all available written literature, there should be no cross effect between the two drugs.
However, and as we have been surprised before, in order to completely exclude that you need to have a formal double blinded study with statistically acceptable results to formally say that these two drugs do not interact with each others.

Michele S. Green, MD · Answer

Botox is a fabulous injection but Benadryl has absolutely no effect on Botox or its longevity.  Botox will last approximately 4 months and no medication that you take will have any effect on it.  Best, Dr. Green

Neda Vanden Bosch, MD · Answer

Hello. I have never heard of Benedryl affecting the longevity of neurotoxins. Maybe you need to increase the dosage you are receiving. That can prolong the longevity.

Does taking Benadryl affect longevity of Botox results?

Answers (11)

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