Is Juvederm Made from Staphylococcus?

i read that juvederm is from staphylocucus . is it true? what about injecting staphylocucus in your body?

Doctor Answers 7

Strep not Staph

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 Yes, Juvederm is derived from a bacterial source, streptococcus equi, not Staphylococcus. Don't worry this is a harmless bacteria species.

Beverly Hills Plastic Surgeon

Most HA fillers are made from streptococcus equii

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Not to worry - Juvéderm and most other hylauronic acid (HA) fillers are made from the bacteria streptococcus equii, not staphylococcus. Juvéderm fillers are safe to use and are approved by Health Canada.

Cory Torgerson, MD, PhD, FRCSC
Toronto Facial Plastic Surgeon
4.7 out of 5 stars 165 reviews

Hyaluronic acid and bacterial source

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Excellent Question. It is true that the hyaluronic acid in Juvederm and most hyaluronic-acid based fillers is derived from bacteria - streptococcus equii. However, there are no harmful bacteria present in the filler product itself.

James M. Pearson, MD
Los Angeles Facial Plastic Surgeon
5.0 out of 5 stars 135 reviews

Juvederm Is Made From a Bacterial Source

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Both Juvederm and Restylane are hyaluronic acid fillers that are derived from bacterial fermentation from specific strains of streptococci. Not to worry. It is highly purified before use and is quite safe.


Mitchell Schwartz, MD
South Burlington Dermatologic Surgeon
4.7 out of 5 stars 12 reviews

Juvederm is made from a bacterial source

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In all species, the hyaluronic acid molecule is the same so we can use hyaluronic acid safely from many sources (as opposed to collagen in which inter species differences made allergy more likely).  The cleanest is to have bacteria manufacture it in the lab for us.  We are not injecting the bacteria, but a product made by them.  There may be minute proteins from the bacteria present but not the organism itsel,f so there is no risk of infection.  Additionally, it is not a staphylococcal strain but a harmless streptococcal strain.  Juvederm is a great product with an excellent safety profile and very low risk of side effects.

Jacqueline Calkin, MD
Sacramento Dermatologic Surgeon

Juvederm made from Streptococcus equii

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The hyaluronic acid in Juvederm is made from Steptococcus equii, a harmless bacteria. Our own body is full of harmless bacteria. Even then don't worry, there is no bacteria or bacterial product/component other than the hyaluronic acid in Juvederm.

Peter T. Truong, MD
Fresno Oculoplastic Surgeon
4.9 out of 5 stars 42 reviews

The HA in Juvéderm [and most other HA fillers] is made by fermentation of Streptococcus Equii

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The HA in Juvéderm [and most other HA fillers] is made by fermentation of Streptococcus Equii.

The bacterial proteins and other non-hyaluronic acid [HA] components are removed during the purification process, leaving an exceptionally pure form of HA.

This pure HA is carefully crosslinked in a very precise manner to give the final product which we know as Juvédern®.

Kevin C. Smith, MD
Niagara Falls Dermatologic Surgeon

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.