When tissue expanders are present prior to radiation therapy it is sometimes necessary to change the volume of one or both expanders in order to deliver optimal radiation. This is a recommendation that would be made by the radiatin ononcologist. It is not always necessary.
Your tissue expanders are there to create enough skin in your breasts so that implants can be placed. Weight loss should not interfere with this process but it's best to talk with your reconstruction surgeon about exactly how you want your breasts to look after you've achieved your weight loss goal.
Staples are generally used to close the skin incision and therefore are usually removed after surgery. However small clips may be used during surgery to prevent blood vessels from bleeding and these are not removed and will show up on imaging studies such as xrays.