This is a very common and reasonable question, and I’m glad you’re thinking about balance rather than just volume. In many cases, a single hyaluronic acid (HA) filler can be safely used across the lips, oral commissures, and piriform fossa during the same session, as long as the product and technique are appropriate. The goal is not simply to add fullness to the lips, but to support the surrounding structures that influence lip shape and movement. For the lips, I typically use a soft, flexible HA filler that integrates smoothly and allows for natural motion. The oral commissures often benefit from gentle support to soften downturning, while the piriform fossa can provide subtle structural support to the upper lip and midface. When these areas are addressed together, the lips often look more natural without requiring an entire syringe placed directly into the lip itself. That said, not all fillers are interchangeable, and not every filler that works well in the lips is appropriate for deeper support areas. Product selection depends on facial anatomy, tissue thickness, and the specific aesthetic goal. Just as important is conservative placement and proper depth, which significantly affect both safety and outcome. In the right patient, thoughtfully distributing a syringe can create a more harmonious and refined result than concentrating all of the product in one area. My philosophy is always to enhance facial balance while preserving natural expression, never to overfill.