I Almost Finish with my 6-month Course of Accutane. How Long After the Course Can I Start Applying Retin-A? How Should I Use It?

Accutane is a go-to medication for patients with recalcitrant cystic acne. It can reduce pore size and also reduce sebum production in your skin, making it less oily; and in turn, dryer. Accutane can be used to control acne, but patients receiving the medication should be carefully monitored. In terms of skincare, always wear an appropriate sunscreen and reduce direct sun exposure. In my patients, I recommend a good ceramide moisturizer such as Elevase whenever they are on Accutane. This will keep the skin hydrated and reduce the oiliness of the skin that is associated with oil-based moisturizers.

Best,
Dr. Karamanoukian
Realself100 Surgeon

In most of my patients, I have them begin a daily topical retinoid regimen a month after they have completed accutane.  This regimen helps keep the pores clear and reduce blemishes and acne scars.  As always, ask your board certified dermatologist what is the best regimen for you.

Many of my patients cannot tolerate a topical tretinoin while on Accutane due to dry skin (especially during a Chicago winter!)  I typically restart topical tretinoin 1-2 months after a patient completes the Accutane treatment, if desired.  Applying a pea-sized amount to the affected areas of the face every other night is a good way to start, increasing to nightly application as tolerated. 

You can begin anytime. In fact, I keep my patients on the mildest forms of Retinioids ( Atralin, Differin cream 0.1 or Retin A 0.04 microgel) while they are on Accutane. Adding a nice moisturizer such as Cerave PM, makes this regimen quite tolerable. There is some evidence that using a Retinoid while on Accutane will help clear blackheads and whiteheads.