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Tri-Luma (fluocinolone, hydroquinone, and tretinoin) is a medication often used to treat melasma, a condition that causes dark patches on the skin. One of the common side effects of Tri-Luma is skin color changes, including lightening or darkening of the skin.The uneven lightening you're seeing could be a result of the medication working on different areas of pigmentation at different rates. However, if you're noticing significant unevenness or if the lightening is occurring in areas where you didn't have dark patches to begin with, it would be a good idea to consult with your dermatologist. They may advise you to discontinue or adjust the way you're using the medication.Remember, it's important not to stop using the medication abruptly without consulting your doctor first. They will be able to guide you on how to safely discontinue its use if necessary, or adjust the treatment plan to better suit your needs.In the meantime, continue to protect your skin from the sun, as sun exposure can worsen melasma and counteract the effects of the medication. Use a broad-spectrum sunscreen with an SPF of 30 or higher every day, and reapply it every 2 hours or immediately after swimming or sweating.
