Hydroquinone during IVF egg retrieval?

Question

Hello, Is it safe to use ingredients such as hydroquinone, retinol, TCA peel, etc., while doing an egg retrieval for IVF, especially if I am not planning to be pregnant. We have to use a surrogate for pregnancy, but I am using my own eggs. Can these ingredients affect the eggs in my ovaries?

Anna Chacon, MD, FAAD · Answer

When undergoing IVF and egg retrieval, it's essential to consider the potential effects of skincare ingredients on your overall health and the health of your eggs. While hydroquinone, retinol, and TCA peels are primarily topical treatments, it's always best to exercise caution. Here is some guidance regarding these ingredients:

Hydroquinone: This is a skin-lightening agent used to treat hyperpigmentation. There is limited data on its systemic absorption and effects on egg quality, but it's generally recommended to avoid any unnecessary exposure to potentially harmful substances during IVF.

Retinol (Vitamin A derivatives): High doses of Vitamin A, including retinoids, are known to have teratogenic effects, which is why they are typically avoided during pregnancy. While topical application results in lower systemic absorption, it is advisable to discontinue use during the egg retrieval process to be safe.

TCA Peels (Trichloroacetic Acid Peels): These chemical peels penetrate deeper into the skin, but systemic absorption is minimal. However, due to the lack of specific studies on TCA peels and egg retrieval, it might be prudent to avoid them during this sensitive period.

Given the importance of ensuring the best possible environment for your eggs, you should consult with your fertility specialist or dermatologist for personalized advice. They can provide guidance based on the latest research and your specific situation.

Best wishes with your IVF journey.

Hydroquinone during IVF egg retrieval?

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