These are definitely two different devices! I demo'ed both in my office and found the silkpeel (also known as the dermal infusion) to be superior. Both clean your skin and vacuum out your pores and then infuse various treatments to the skin. The big difference is the hydrafacial saturates the "skin surface" (that is a quote from their website,) while the dermal infusion actually infuses the treatment past the surface to the dermis. That way, when you wash your face the evening after the treatment you can't wash off the dermal infusion treatment--whether it was vit C, salc acid, hyaluronic acid, etc, it stays in the skin and keeps working. The hydrafacial gets a lot of press and has a big marketing budget but it is not equivalent to a dermal infusion. If a good cleaning is what you are after, both do a good job, and either is fine. If you want a treatment to help fix a certain problem the dermal infusion is the way to go. Hope this is helpful, Dr. Amy