Squamous cell carcinoma (SCC) begins in the epidermis or upper dermis, but if left untreated, it can invade deeper structures, including the cartilage or even bone of the nose. Most SCCs are caught early and remain confined to the skin layers. Certain factors—like larger size, recurrent tumors, aggressive histologic subtype, or involvement of the tip/alar rim—increase the risk of deeper invasion. That’s why Mohs surgery is often recommended for nasal SCC: it allows the surgeon to completely remove the tumor layer by layer while sparing healthy tissue, and also ensures that any deeper invasion is detected and treated. In short, while many SCCs stay in the skin, deep structures like cartilage can be involved if the tumor is aggressive or long-standing, so careful treatment is important.