Why must Botox be reconstituted using 21 gage needle? What happens if larger 18 gage or smaller 25 gage is used?
Answer: Why must Botox be reconstituted using 21 gauge needle? What happens if 18 gauge or 25 gage is used? Thank you for your excellent question. Reconstitution of Botox involves placing a saltwater solution into the prepackaged vial of dried product, using whatever size needle that the injector wishes. Once ready for injection a smaller gauge (typically a 29 or 30) is used to administer the Botox to patients. This maximizes comfort and minimizes potential issues, such as bruising.
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Answer: Why must Botox be reconstituted using 21 gauge needle? What happens if 18 gauge or 25 gage is used? Thank you for your excellent question. Reconstitution of Botox involves placing a saltwater solution into the prepackaged vial of dried product, using whatever size needle that the injector wishes. Once ready for injection a smaller gauge (typically a 29 or 30) is used to administer the Botox to patients. This maximizes comfort and minimizes potential issues, such as bruising.
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Answer: Botox reconstitution Thank you for your question jerronba. Botox is a purified protein used to address wrinkles associated with facial expression. It comes as a dry powder in 50 unit or 100 unit vials. The manufacturer recommends reconstituting Botox in 2.5 mL of saline for 100 units. The gauge of the needle does not matter. Larger needles (smaller numbers) will allow the saline to pass through faster than smaller needles (smaller sizes). We use 27 Ga needles to reconstitute the Botox and 30 Ga needles for injections. Many doctors use larger needles for reconstitution. Please consult with a doctor for specific recommendations. Good luck!
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Answer: Botox reconstitution Thank you for your question jerronba. Botox is a purified protein used to address wrinkles associated with facial expression. It comes as a dry powder in 50 unit or 100 unit vials. The manufacturer recommends reconstituting Botox in 2.5 mL of saline for 100 units. The gauge of the needle does not matter. Larger needles (smaller numbers) will allow the saline to pass through faster than smaller needles (smaller sizes). We use 27 Ga needles to reconstitute the Botox and 30 Ga needles for injections. Many doctors use larger needles for reconstitution. Please consult with a doctor for specific recommendations. Good luck!
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November 9, 2016
Answer: Botox and Reconstitution It does not matter what size the needle used to reconstitute the Botox with. Only what product you use to dilute the Botox. Best, Dr. Green
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November 9, 2016
Answer: Botox and Reconstitution It does not matter what size the needle used to reconstitute the Botox with. Only what product you use to dilute the Botox. Best, Dr. Green
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July 28, 2016
Answer: Reconstitution of Botox When Botox was first introduced as Botox Cosmetic, the company was somewhat emphatic about how it was to be reconstituted. The training courses back in the late middle 1990's indicated that the molecules were somewhat fragile and that allowing a quick jet of saline to hit the Botox molecules could damage them. The recommendation was to use a 21 or 22 gauge needle and resist letting the plunger pull down quickly. We replaced a nurse in the clinic who didn't do it that way and we had two vials that got injected where patients had a much poorer response and had to be re-injected. I think its a difference that probably makes a difference. We also use preservative free normal saline to reconstitute.
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July 28, 2016
Answer: Reconstitution of Botox When Botox was first introduced as Botox Cosmetic, the company was somewhat emphatic about how it was to be reconstituted. The training courses back in the late middle 1990's indicated that the molecules were somewhat fragile and that allowing a quick jet of saline to hit the Botox molecules could damage them. The recommendation was to use a 21 or 22 gauge needle and resist letting the plunger pull down quickly. We replaced a nurse in the clinic who didn't do it that way and we had two vials that got injected where patients had a much poorer response and had to be re-injected. I think its a difference that probably makes a difference. We also use preservative free normal saline to reconstitute.
Helpful 2 people found this helpful
January 13, 2016
Answer: Botox Reconstitution Dear jerronba,Botox is reconstituted using salt water prior to injection. This can be performed using any appropriate size needle.Injection is commonly performed using a very small needle. I prefer to use a 32 gage needle that is commonly called a nanoneedle.Warmest wishes,Larry Fan, MD
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January 13, 2016
Answer: Botox Reconstitution Dear jerronba,Botox is reconstituted using salt water prior to injection. This can be performed using any appropriate size needle.Injection is commonly performed using a very small needle. I prefer to use a 32 gage needle that is commonly called a nanoneedle.Warmest wishes,Larry Fan, MD
Helpful 1 person found this helpful
