Not responding to Botox (Azzalure) - what are my options?

Question

Hi! I’m a 25 year old female and I’ve only had Botox now three times. The first time it worked really well, it was a bit much. I waited maybe 3 years before trying Botox again. And it didn’t work, even when I went back after 4 weeks for a higher dosage. A year after this I tried again. Went back two times with 4 weeks apart both times, and it didn’t work. The doctor suggested I try another brand. The brand that isn’t working on me is Azzalure. Can I try Xeomin or does it have to be Dysport?

Rita Rakus, MBBS · Answer

Hello and thank you for your question. It is always best to see you face to face for a consult and examination however in this case the usual issue is dose- the injector needs t be confident in delivering a high enough dose which will work for you. It's rare for toxin to be completely ineffective. I hope that helps answer your question. Always seek an experienced and qualified medical professional for these treatments. Very best wishes

Alan Gonzalez, MD, FACS · Answer

Hello @Viiktoriaaa thank you for your question. I suggest you consult with a specialist to asses your case, it is rare for a person to develop immunity to botox but it is within the realm of possibility. To know for sure if you need Dysport or Xeomin the specialist has to evaluate your skin type, how those lines are made, how deep they go, what your expectations are and how the product is applied. best wishes! Alan Gonzalez MD

Ayham Al-Ayoubi, MD, MS, DLO RCS · Answer

I have been using all types of anti-wrinkle injections - Botulinumtoxin type A ( Botox, Azzalure, Xeomin Dysport, Allergan and Bocouture ) for more than 22 years. The brand has no roll in your case. Most likely it was a faulty vial.

Camille Cash, MD · Answer

You can try either Xeomin or Dysport as alternatives to Botox.  Be sure you are seeing an expert injector for your treatment and that the number of units is appropriate for the area.  I've included a video on neuromodulators that I hope you find helpful.

Jason Emer, MD · Answer

If Botox is not an option for you, Dysport or Xeomin are the next options. I suggest dermarolling at home to give the skin Botox-like effects with at-home treatment. See an expert. Best, Dr. Emer

Not responding to Botox (Azzalure) - what are my options?

Answers (7)

Answer: Botox

Answer: Botox

Answer: Botox Resistance

Answer: Botox Resistance

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Not responding to Botox (Azzalure) - what are my options?

Answers (7)

Answer: Botox

Answer: Botox

Answer: Botox Resistance

Answer: Botox Resistance

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Recommended reading

Everything you need to know about Botox

Our mission is to create a world where every investment in modern beauty is Worth It.