Each time the cream is applied, I get strange sensations through my body and my entire face immediately turns bright red (before the actual treatment) and stays that way for one to two weeks following non-ablative fraxel treatments. I am interested in dermal fillers for acne scarring and wrinkles but am concerned about reacting to the pain medications in the fillers. Should I have a skin test to check for allergic reactions before I proceed with any fillers?