Hi Leslie. I appreciate your concern with regard to neuropathic conditions that require cautionary use of Botox. The simple answer is to try the Belotero first for both the horizontal forehead and vertical glabellar lines. Its usually safe, easy, and effective for about 3- 9 months, depending largely on how often you wrinkle your forehead. Belotero is usually my first choice for treatment of etched-in static wrinkles For deeper creases or folds, fillers with higher G prime, such as juvyderm ultra plus and sometimes Radiesse may be judiciously employed. Recently, for dynamic wrinkles, another non-surgical alternative to Botox that has been introduced is the radiofrequency, high energy device called Thermi Rase. It is designed to “zap” the ( temporal ) nerve branches that move your (frontalis,procerus, and corrugator) muscles. This serves to reduce forehead wrinkling for about a year according to some reports. Don's discredit Botox entirely - especially for dynamic unwanted expression lines, like the glabellar frown lines. There are some neurologic conditions where Botox may be considered in rare circumstances and with many warnings or caveats. An example of such a peripheral motor neuropathy is myasthenia gravis(MG). In such conditions, one must localize the effect to purely the offending muscle very conservatively. One therefore starts a with minimal dose in high concentration to limit the spread of the Botox to only the offending muscle. It should be mentioned, that with these precautions, the effect of Botox in MG has been reported to last as long as eighteen months, instead of 2-4 months. I hope this gives some perspective to your choices. At the end of the day, it is always wise to consult a Board Certified Plastic Surgeon or other Core Specialist when there are any medical concerns.A forehead lift to smooth out redundant skin along with static and dynamic wrinkles is the gold standard. Everyone deserves the most experienced and knowledgeable approach to best meet their aesthetic goals. All the best.