Where to Get Botox Injected for Horizontal Lip Line?

The depressor nasi septi muscle which is responsible for plunging of hte nasal tip with smiling can be injected with botox at the base of the columella.

Please make sure that you evaluate any response from a physician who is not examining you in person, my response as well, with caution. You are discussing a horizontal line, not vertical line. Some people get this when they smile. It may not be the depressor nasi muscle. Injecting Botox to minimize contraction of the risorius or zygomatic muscles could create several months of disturbing facial appearance and difficulty with eating and speech. The off-label use of Botox in this area should be done by an expert and sometimes the one unit injected in the mid cutaneous upper lip in 2 to four areas may be enough to minimize the crease...but if you are unhappy with the result, you will have to deal with it for three to four months possibly.

If surgery is not an option (you need to see a plastic surgeon to determine this), laser resurfacing could be an excellent option.  Laser resurfacing can soften eliminate lines in this area.  (see examples of this in my photos that I have posted on RealSelf).  Seek out a dermatologist in your area with lots of laser experience, particularly in the use of CO2/Erbium lasers.  Take care, Dr. Groff