Is it true if you work out in gym release the Botox quicker?

In my opinion, working out or exercising would in no way effect your results from Botox, or any other neuromodulator for that matter. 

This is a heavily debated topic.  I don't feel that your body metabolizes the Botox more quickly with exercise; however, what may be happening is you are moving muscles that are not affected by Botox during exercise, which may give the appearance of decreased Botox duration.

If
you were to exercise at the gym and you were using your facial muscles more
while exercising, for example, frowning, squinting, or lifting your eyebrows,
you may find that the effect from your Botox treatment does not last as long,
since you are forcing the use of the muscles that were relaxed with the Botox.

The effect of Botox is to alter the nerve's ability to send signals to it's muscles.  Working out does not change this physiology.  However, what my be happening (in theory) is that as you work out, you're strengthening the other surrounding muscles that have not been affected by BOTOX (if there are some ) and they become stronger and compensate for the relaxed muscles which are still under the effect of your Botox injection

Most doctors will say that exercise or expression have no effect on botox longevity, however, I have treated a lot of men, a lot of expressive people, and lot of people that exercise and I have found that the botox/dysport/xeomin does not last as long as it does in people who are not in those categories.  Either get touch ups sooner or get larger doses when you first get treatment.  Best, Dr. Emer.

Hello danielo,The answer to your question is NO.  The duration of the effect of Botox can vary from patient to patient.  With repeated, regular doses of Botox, some patients develop enough muscle atrophy that their results start to extend their duration.  I have several patients that now only come to see me once a year to get their Botox.  With repeated doses of Botox, some patients develop antibodies to the Botox protein that causes their duration of action to get shorter.  These patients notice that the Botox no longer lasts as long, or they need more Botox to overpower the muscles to get the results they want.  I advocate for patients to get on a regular Botox schedule every 3 months for at least a year to see if long term atrophy can be created.  It is my belief that random applications of Botox at irregular intervals create the greatest treatment failures over time.  The effect of Botox wears off when the antibodies decrease local toxin concentration, or when the muscle "grows" more neuromuscular junctions that can respond to normal neurotransmitter stimulation, effectively bypassing the Botox treated areas.  With that said, have a great workout!Dr. Shah

Without a doubt, 100% Not true. Those who understand the physiology of Botox (botulinum toxin) on a molecular level know this is the case. Exercising has absolutely no effect on the duration of action of the medication. The way Botox works, simply put is it is actually taken up in a nerve cell and then it prevents the nerve cell from releasing a chemical that causes your muscle to contact. Hence, you can no longer contact and thus your facial muscles relax. After 2-3 months, your nerve ends up sprouting new branches to re-innervate the muscle. All nerve fibers grow at a similar rate and thus it should theoretically take the same amount of time.  Botox is not "metabolized" by your nerves. Your nerves need to re-sprout little connections (axons) to get back to normal. Perhaps one would argue that if you continuously TRIED to contract your facial muscles for 2 months you may stimulate your brain to start working to repair the nerve quicker, but that would be solely theoretical. So, to answer your question, absolutely not. Keep Exercising!Dr James P. BonaparteOtolaryngology - Head and Neck SurgeryFacial Plastic and Reconstructive SurgeryOttawa, Ontario, Canada

This is a heavily debated topic. In my experience, a lot depends on how strenuous the workout is. If you have aggressive workouts, then it is possible to speed up your metabolism which does consume what you put in your body (e.g. food, botox, medicine, etc.). However, most patients do not work out at a level that it makes a significant difference.

If you workout, your metabolism speeds up. When your metabolism speeds up, you metabolize anything you put in your body more quickly, such as food, medicine, Botox Cosmetic® and even facial dermal fillers, such as Restylan ®.

No.  Whether you exercise or not, the duration of Botox effect is determined by the dose given (in units), the areas injected, the technique of injection, and the rate at which your body metabolizes Botox.  Once the Botox "binds" to the nerve cell, exercise will not affect its duration of action.  Will you need more units of Botox given more frequently if your BMI continues to decrease with exercise? Maybe.  Good luck.