When using santyl is it normal for a smell when changing the bandage?

I appreciate your question.
Santyl is a collagenase debridement ointment used under a doctor's supervision for wound care. In all wounds, there can be odors forming, but I cannot tell if it's the Santyl or the wound. I suggest a full assessment by your prescribing doctor.
Good luck. Dr. ALDO  

Always best to have dressing changes with your PS who can examine the wounds during the dressing change. Every dressing often smells but the crucial thing is how the wound is.