Renuva: What You Need to Know

Medically reviewed by Stanley Okoro, MDBoard Certified Plastic Surgeon
Written byKaryn RepinskiUpdated on February 21, 2024
RealSelf ensures that an experienced doctor who is trained and certified to safely perform this procedure has reviewed this information for medical accuracy.You can trust RealSelf content to be unbiased and medically accurate. Learn more about our content standards.
Medically reviewed by Stanley Okoro, MDBoard Certified Plastic Surgeon
Written byKaryn RepinskiUpdated on February 21, 2024
RealSelf ensures that an experienced doctor who is trained and certified to safely perform this procedure has reviewed this information for medical accuracy.You can trust RealSelf content to be unbiased and medically accurate. Learn more about our content standards.

Fast facts


Renuva Mobile (1)
Renuva Mobile (1)

Renuva is an injectable treatment that can reverse volume loss in the face and neck, to plump cheeks, smooth wrinkles, and improve skin tone.

It can also rejuvenate the backs of hands, balance asymmetrical breasts, and fill in indented scars, cellulite dimples, décolletage lines, and liposuction irregularities.

Once injected, Renuva creates a honeycomb-like "adipose matrix" that acts as a scaffold for your own body fat to form, a process called remodeling. It's gradually replaced over the next three months by your own fat cells, reversing volume loss in the face, hands, and body.

“Renuva relies on your own body’s ability to replace fat within the injected structural matrix material,” explains Dr. Erez Sternberg, a plastic surgeon in Jacksonville, Florida.

Results are similar to autologous fat transfer (in which excess fat is harvested from another area of the body and injected into an area where more volume is desired), without the need for liposuction. This can be a plus for people who have little body fat to transfer, or who don’t want the risks or expense of plastic surgery.

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Pros

  • Renuva can reverse fat loss and add volume in any areas of the body where fat naturally exists, including the face, hands, breasts, and buttocks.
  • It can effectively treat a wide range of concerns, including cellulite dimples, breast asymmetry, breast implant rippling, and indentations from scars.
  • The treatment is done in-office and requires no downtime.
  • Results can be very natural looking, since the volume is created by your own new fat cells. 
  • While you'll continue to age, the new fat that develops will be permanent (while other injectable dermal fillers offer only temporary results).
  • Renuva works especially well for small volume improvements, such as filling in divots and dimples.
  • Renuva is less expensive and less invasive than fat transfer, a surgical procedure that requires liposuction.

Cons

  • While you’ll see some immediate results, it takes up to three months to see final results. 
  • You may need more than one Renuva treatment for optimal results.
  • Results are dose-dependent and can vary, so it’s important to find an experienced provider. 
  • Unlike with temporary dermal fillers, results aren’t easily reversible.

Related: I Tried Renuva to Make My Hands Look More Youthful—Here’s My Honest Review

  • Average Cost:
  • $2,025
  • Range:
  • $1,200 - $4,800

Your cost will depend on how many ccs you get, how many treatment sessions you have, your provider’s level of experience, and their practice location.

You can finance your treatment with CareCredit.

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The Renuva photos in our gallery have been shared by the provider who performed the procedure, with the patient's consent.

Renuva is an allograft adipose matrix, meaning it's derived from purified donated fat tissue. 

The Renuva adipose matrix contains the same growth factors, proteins, and collagen found in your own naturally occurring fat, so your body won’t react to Renuva as a foreign substance.

Renuva injections are an in-office procedure that typically takes 30 to 60 minutes, depending on the number of areas of the body being treated. 

The procedure itself is very straightforward:

  • First, the treatment areas will be numbed with a local anesthetic.
  • Once the area is numb, Renuva is injected under your skin via a small needle or cannula. 

Recovery time is short: you’ll be able to return to work or daily activities immediately afterward.

You’ll see some smoothing and additional volume right away, but it takes up to three months to see your final result, according to Dr. Stanley Okoro, a plastic surgeon in Marietta, Georgia. That’s how long it takes for your own body fat to fill in the adipose matrix.

If you decide you don’t like your Renuva results, the deoxycholic acid in Kybella can melt the fat. It can also be removed via liposuction.

No major side effects have been reported.

As with other injectable procedures, there’s potential for swelling, tenderness, redness, bruising, pain, or irritation at the injection site during the initial recovery period.

Any of these symptoms should resolve on their own after a few days.

It’s possible that you’d need two or more Renuva treatments to get the results you want. Dr. Jason Emer, a plastic surgeon in West Hollywood, California, recommends a series of injections until you see optimal results. At your first treatment session, your provider will inject a baseline amount.

You’ll return three months later, once your body’s own fat has filled in the treated area, to assess your results and determine whether another treatment is needed.

Renuva results are permanent. While the Renuva adipose matrix itself is not permanent, “your own fat that settles into the matrix will be,” says Dr. Okoro.

There are no live cells in Renuva, so it’s not the same thing as getting a live fat transfer. During an autologous fat transfer procedure, the surgeon harvests fat cells from one area of your body via liposuction. The fat is then processed before being injected into another area, such as the breasts, butt, or face. 

“If you’re looking for volume, nothing beats a live fat transfer,” says Dr. Hung William Song, a physician in Oakland, New Jersey, in a RealSelf Q&A. “If you are looking for some rejuvenation of the skin and modest plumping of the skin, an off the shelf product like Renuva is easy to use.” 

When you don’t have enough excess volume for fat transfer from other areas of your body , or you want to avoid the expense and risks of harvesting it via liposuction, Renuva is a viable option.

“It’s a great alternative for patients who are too thin to use their own fat or who need only a small amount of fat—like those needing around 5cc [less than 0.2 ounces], to improve the look of cellulite in the thighs, correct small defects in the breasts, or add facial volume,” says Dr. Sternberg.

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Updated February 21, 2024

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From the manufacturer

Renuva is a groundbreaking aesthetic treatment that, when injected, gradually replaces age-related fat loss with your body’s own fat. Renuva is the ideal solution to restore age-related volume loss in the face and hands, as well as other areas of the body. Renuva also improves small contour deficiencies in the buttocks, hip-dips, and smoothes body irregularities related to cellulite dimples, liposuction, breast rippling caused by surgery and/or breast imbalances.

Learn more about Renuva

From the manufacturer

Renuva is a groundbreaking aesthetic treatment that, when injected, gradually replaces age-related fat loss with your body’s own fat. Renuva is the ideal solution to restore age-related volume loss in the face and hands, as well as other areas of the body. Renuva also improves small contour deficiencies in the buttocks, hip-dips, and smoothes body irregularities related to cellulite dimples, liposuction, breast rippling caused by surgery and/or breast imbalances.

Learn more about Renuva

Real Renuva results

Real Renuva results

Watch these videos from Renuva

What Is Renuva & How Does It Work?

Renuva is a groundbreaking, off-the-shelf treatment that replenishes age-related volume loss in the face, neck and hands, camouflages breast rippling caused by surgery, small volume buttocks contouring, smooths liposuction irregularities, erases cellulite dimples and flattens depressed scars. When Renuva is injected, it creates a honeycomb-like matrix that, over the course of three months post treatment, dissolves and is replaced by your body’s own fat – exactly where you want it, so the final look is still you, only better!

Dr. Leif Rogers Answers Your Questions About Renuva

World-renowned, board-certified plastic surgeon Dr. Leif Rogers answers popular questions from RealSelf patients about Renuva:

• How long does Renuva last?

• Can Renuva be used in the face?

• Can Renuva improve my neck?

• Can Renuva be injected into the lips?

• What are the long-term effects and outcomes of Renuva

• Is Renuva an option for skinny-fat patients?

• Can Renuva be used to fill out my butt and hips?

• Can Renuva correct botched liposuction?

• Can Renuva be used in breast reconstruction?

Watch a Full-Face Renuva Treatment with The Master Injector

Elite nurse injector and Renuva trainer, Bernice Cohen (also known as The Master Injector), RN, BSN, PHN, CANS, explains where to inject Renuva on the face to plump, lift and rejuvenate. Cohen demonstrates Renuva being injected into the midface, chin, nasolabial folds, jawline and temples.


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