Can a Kenalog Injection into the Nose Lead to Cartilage Atrophy?

Can 0.2 ml of kenalog 20 injected 6 months after rhinoplasty dissolve cartilage? Thanks

Doctor Answers 3

Kenaolog is unlikely to cause atrophy of cartilage

I did a medline search looking for cause and effect of intralesional kenalog and complications induced in cartilage.  I was unable to find even a single case report noting this association.  I was able to find literature on decreased cartilage matrix degradation if short-term systemic steroids are used to decrease the inflammatory process induced by injury.  I have included a link for you on this.  So, to answer your question I would say no, particularly if the injection was performed to shut down inflammation.  Also, 0.2 ml at 20 units/cc, is a total of 4 units of Kenalog, which is not a large dose.  I hope this helps!


Las Vegas Dermatologist
5.0 out of 5 stars 3 reviews

Kenalog injection after rhinoplasty

Kenalog may cause dermal atrophy (thinning of the skin), but it will not affect the cartilage.  

Donald B. Yoo, MD
Beverly Hills Facial Plastic Surgeon
5.0 out of 5 stars 24 reviews

Kenalog injection into nose should not dissolve cartilage

Kenalog injections are not injected into the cartilage.  They are injected into the dermis.  Depending upon the concentration that is used, dermal atrophy can occur, so we always use a very light concentration of cortisone to dissolve scar tissue and prevent fluid buildup in the first few months after the surgery.  A cortisone shot does not dissolve cartilage and works best only within the first few months after surgery, not years after.

William Portuese, MD
Seattle Facial Plastic Surgeon
5.0 out of 5 stars 62 reviews

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