Hello, We've had different patients with various levels of pain tolerance. Most of the people are able to tolerate it without anything. Ibuprofen is suggested by the manufacturer. Ultherapy is marketed as the "lunch time" procedure and with that you should be able to go through that without any problems. With all other medications you will need to have someone take you home.
Despite everything you may read on the internet, in my experience most of my patients tolerate the Ultherapy treatment very well without any medication at all. That being said, if I believe the patient is very sensitive, I prescribe Valium (Diazepam) 5 mg and Percocet 5/325 prior to the procedure. I would stay away from aspirin or aspirin containing products as some of my patients have had mild to moderate bruising with these products.