Cause of Allergic Reaction to Restylane?

Thank
you for your question. It’s very rare to have an allergic reaction to
hyaluronic acid fillers, such as Restylane or Juvederm. Your reaction is most
likely due to the ingredients in hyaluronic acid products and this is very
common. However,
I do recommend having a follow up with injector to have this evaluated and
treated. Best of Luck!

Granulomas are when the body reacts to a substance and considers it foreign material. The is an intense inflammatory response, but not an allergy. This creates redness and swelling. Steroids are usually given to reduce the swelling. Sometimes, dissolving the filler with hyaluronidase will resolve the problem too.
You can form granulomas with any filler. Also, it doesn't happen every time you get the same filler.
Interesting, I was told that Radiesse forms the least amount of granulomas of the fillers, but I can't substantiate that. Radiesse does form more nodules than other fillers, which is bumps that are not swollen and do not hurt.
I don't have any personal experience with the granulomas, but have been to several meetings where they were discussed.