How wet should my lashes be when applying Latisse?

You want your eyelashes first to be clean from any make-up and oils. Once your eyelashes are dry you should put one to two drops of Latisse on the eye brush. This will make your eyelashes damp. If you have any excess Latisse use a Q-tip or tissue to absorb  the remaining product. 

You want to make sure that you've removed all of your eye makeup before latisse to your dry/damp lashes. Obviously, the latisse will make them wet. Make sure to clean up any excess product with a q-tip. Best, Dr. Nazarian

Latisse should be applied to the lash line, not the lashes themselves. And the lashes should be dry prior to application.