Hi Priya, There is no permanent Botox or other form of injectable botulinum toxin. However, since Botox keeps you from being able to contract your facial muscles as much as you were able to before you had Botox, these muscles temporarily soften/weaken (atrophy). I liken it to what one's leg looks like when a cast has been removed. If you've ever seen someone's leg after wearing a cast, the injured leg looks a lot thinner than the non-injured leg. This is because the muscles weaken (become "atrophic") because they haven't been able to contract for a prolonged period while the person was wearing the cast. This analogy applies to the muscles in the face and how they become thinner/atrophic over time with Botox injections. The first few times you get Botox, it typically lasts 3-4 months. However, if you are good about coming in for re-treatment (with more Botox injections) as soon as you start to notice those wrinkles reappearing, those facial muscles are then not able to get as strong as they were before you started getting Botox and the effects of the Botox will last longer. For example, some of my patients who have been getting Botox for years (and return for re-treatment as soon as their wrinkles start to reappear) can space their visits 9 or more months apart because those muscles are so "wimpy"/atrophic/weak. Hope this helps. Good luck!