OK- the answer not only lies in the laser but the settings and other treatments. Do I use the Mediate C6? Yes, I use this under a vvv low fluence using no end points and large spot sizes, every 2 weeks, for at least 6 sessions. Other lasers such as PICOSURE work better in most cases. Melasma can not be completely cured, however effective treatment are possible. This is because your skin is extremely sensitive to UV and even the smallest amount can stimulate your pigment cells to produce colour. The mainstay of treatment is strict UV protection- hats, sunglasses and SPF every 4 hours. I prefer to use a combination of creams and laser for melasma. Hydroquinone can be used (5-8%), along with vitamin A creams. I usually start my patients on laser (low dose Q switch or Picosure) a few weeks after they commence on creams. In some cases I combine glycolic AHA peels, and in other cases I use a tablet called Tranexamic acid to help. More information in the video WEB REFERENCE All the best, Dr Davin Lim Laser, surgical and aesthetic dermatologist Brisbane, Australia